BDBM50072024 (11R,13S,14S,17S)-11-(4-Dimethylamino-phenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one::CHEMBL438575::Korlym::Mifegyne::Mifeprex::Mifepristone

SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C

InChI Key InChIKey=VKHAHZOOUSRJNA-RFXZOGDSSA-N

Data  1 KI  1 IC50

PDB links: 7 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50072024   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072024((11R,13S,14S,17S)-11-(4-Dimethylamino-phenyl)-17-h...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity against human progesterone receptor-A (hPR-A)More data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072024((11R,13S,14S,17S)-11-(4-Dimethylamino-phenyl)-17-h...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity against human progesterone receptor B (hPR-B) in cotransfected CV-1 cellsMore data for this Ligand-Target Pair